Ontology highlight
ABSTRACT:
SUBMITTER: Di Luigi L
PROVIDER: S-EPMC4883282 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Di Luigi Luigi L Corinaldesi Clarissa C Colletti Marta M Scolletta Sabino S Antinozzi Cristina C Vannelli Gabriella B GB Giannetta Elisa E Gianfrilli Daniele D Isidori Andrea M AM Migliaccio Silvia S Poerio Noemi N Fraziano Maurizio M Lenzi Andrea A Crescioli Clara C
Inflammation 20160601 3
T helper 1 (Th1) type cytokines and chemokines are bioactive mediators in inflammation underling several diseases and co-morbid conditions, such as cardiovascular and metabolic disorders. Th1 chemokine CXCL10 participates in heart damage initiation/progression; cardioprotection has been recently associated with sildenafil, a type 5 phosphodiesterase inhibitor. We aimed to evaluate the effect of sildenafil on CXCL10 in inflammatory conditions associated with diabetic cardiomyopathy. We analyzed: ...[more]