Crohn's disease complicated by strictures: a systematic review.

ABSTRACT: The occurrence of strictures as a complication of Crohn's disease is a significant clinical problem. No specific antifibrotic therapies are available. This systematic review comprehensively addresses the pathogenesis, epidemiology, prediction, diagnosis and therapy of this disease complication. We also provide specific recommendations for clinical practice and summarise areas that require future investigation.

SUBMITTER: Rieder F 

PROVIDER: S-EPMC4884453 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature