The effect of diet and time after bacterial infection on fecundity, resistance, and tolerance in Drosophila melanogaster.

ABSTRACT: Mounting and maintaining an effective immune response in the face of infection can be costly. The outcome of infection depends on two host immune strategies: resistance and tolerance. Resistance limits pathogen load, while tolerance reduces the fitness impact of an infection. While resistance strategies are well studied, tolerance has received less attention, but is now considered to play a vital role in host-pathogen interactions in animals. A major challenge in ecoimmunology is to understand how some hosts maintain their fitness when infected while others succumb to infection, as well as how extrinsic, environmental factors, such as diet, affect defense. We tested whether dietary restriction through yeast (protein) limitation affects resistance, tolerance, and fecundity in Drosophila mel

SUBMITTER: Kutzer MA 

PROVIDER: S-EPMC4884575 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature