Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.
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ABSTRACT:
SUBMITTER: Rodius S
PROVIDER: S-EPMC4886216 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.
Rodius Sophie S Fournier Anna A Götz Lou L Liechti Robin R Crespo Isaac I Merz Susanne S Nazarov Petr V PV de Klein Niek N Jeanty Céline C González-Rosa Juan M JM Muller Arnaud A Bernardin Francois F Niclou Simone P SP Vallar Laurent L Mercader Nadia N Ibberson Mark M Xenarios Ioannis I Azuaje Francisco F
Scientific reports 20160531
The zebrafish has the capacity to regenerate its heart after severe injury. While the function of a few genes during this process has been studied, we are far from fully understanding how genes interact to coordinate heart regeneration. To enable systematic insights into this phenomenon, we generated and integrated a dynamic co-expression network of heart regeneration in the zebrafish and linked systems-level properties to the underlying molecular events. Across multiple post-injury time points, ...[more]
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