Ontology highlight
ABSTRACT:
SUBMITTER: Ponti G
PROVIDER: S-EPMC4888015 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Ponti Giovanni G Pellacani Giovanni G Martorana Davide D Mandel Victor Desmond VD Loschi Pietro P Pollio Annamaria A Pecchi Annarita A Dealis Cristina C Seidenari Stefania S Tomasi Aldo A
Oncology letters 20160419 6
Elephantiasis neuromatosa (EN) can arise from a plexiform neurofibroma of the superficial and deep nerves developing from a hyperproliferation of the perineural connective tissue infiltrating adjacent fat and muscles. To date, the clinical association between EN and neurofibromatosis type 1 (NF1) has been poorly defined, particularly with regard to the role of lymphatic alterations and the consequent lymphedema. The present study reports the clinical and biomolecular features of EN in a NF1 pati ...[more]