Dataset Information

Derivation and Validation of a Modified Short Form of the Stroke Impact Scale.

ABSTRACT:

Background

The Stroke Impact Scale (SIS) is a stroke-specific, quality of life measure recommended for research and clinical practice. Completion rates are suboptimal and could relate to test burden. We derived and validated a short form SIS (SF-SIS).

Methods and results

We examined data from the Virtual International Stroke Trial Archive, generating derivation and validation populations. We derived an SF-SIS by selecting 1 item per domain of SIS, choosing items most highly correlated with total domain score. Our validation described agreement of SF-SIS with original SIS and the SIS-16 and correlation with Barthel Index, modified Rankin Scale, National Institutes of Health Stroke Scale, and Euro-QoL 5 dimensions visual analog scales. We assessed discriminative validity (associations between SF-SIS and factors known to influence outcome [age, physiological parameters, and comorbidity]). We assessed face validity and acceptability by sharing the SF-SIS with a focus group of stroke survivors and multidisciplinary stroke healthcare staff. From 5549 acute study patients (mean age 68.5 [SD 13] years, mean SIS 64 [SD 32]) and 332 rehabilitation patients (mean age 65.7 [SD 11] years, mean SIS 61 [SD 11]), we derived an 8-item SF-SIS that demonstrated good agreement with original SIS and good correlation with our chosen functional and quality of life measures (all ?>0.70, P<0.0001). Significant associations were seen with our chosen predictors of stroke outcome in the acute group (P<0.0001). The focus group agreed with the choice of items for SF-SIS across 7 of 8 domains.

Conclusions

Using multiple, complementary methods, we have derived an SF-SIS and demonstrated content, convergent, and discriminant validity. This shortened SIS should allow collection of robust quality of life data with less associated test burden.

SUBMITTER: MacIsaac R

PROVIDER: S-EPMC4889183 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Publications

Derivation and Validation of a Modified Short Form of the Stroke Impact Scale.

MacIsaac Rachael R Ali Myzoon M Peters Michele M English Coralie C Rodgers Helen H Jenkinson Crispin C Lees Kennedy R KR Quinn Terence J TJ

Journal of the American Heart Association 20160520 5

<h4>Background</h4>The Stroke Impact Scale (SIS) is a stroke-specific, quality of life measure recommended for research and clinical practice. Completion rates are suboptimal and could relate to test burden. We derived and validated a short form SIS (SF-SIS).<h4>Methods and results</h4>We examined data from the Virtual International Stroke Trial Archive, generating derivation and validation populations. We derived an SF-SIS by selecting 1 item per domain of SIS, choosing items most highly correl ...[more]

PMID: 27207963

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Dataset Information

Derivation and Validation of a Modified Short Form of the Stroke Impact Scale.

Background

Methods and results

Conclusions

Publications

Derivation and Validation of a Modified Short Form of the Stroke Impact Scale.

Similar Datasets

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