Ontology highlight
ABSTRACT:
SUBMITTER: Wilson EM
PROVIDER: S-EPMC4889898 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Wilson Eleanor M P EM Tang Lydia L Kottilil Shyam S
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20160601
Chronic hepatitis B infection affects >300 million people worldwide and is a leading cause of liver failure and cancer. Current approaches to treatment for chronic hepatitis B involve suppression of hepatitis B virus (HBV) DNA with the use of nucleoside analogues. Chronic suppressive therapy rarely results in a "functional cure" or absence of detectable HBV DNA in plasma and loss of detectable hepatitis B surface antigen after cessation of therapy. The major obstacles to achieving a functional c ...[more]