Ontology highlight
ABSTRACT:
SUBMITTER: Xie T
PROVIDER: S-EPMC4891100 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Xie Tao T Zhang Lan L Zhang Shouyue S Ouyang Liang L Cai Haoyang H Liu Bo B Liu Bo B
Oncotarget 20160301 9
Autophagy (macroautophagy) is well known as an evolutionarily conserved lysosomal degradation process for long-lived proteins and damaged organelles. Recently, accumulating evidence has revealed a series of small-molecule compounds that may activate or inhibit autophagy for therapeutic potential on human diseases. However, targeting autophagy for drug discovery still remains in its infancy. In this study, we developed a webserver called Autophagic Compound-Target Prediction (ACTP) (http://actp.l ...[more]