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Association of Coronary Stent Indication With Postoperative Outcomes Following Noncardiac Surgery.


ABSTRACT: Current guidelines for delaying surgery after coronary stent placement are based on stent type. However, the indication for the stent may be an important risk factor for postoperative major adverse cardiac events (MACE).To determine whether the clinical indication for a coronary stent is associated with postoperative MACE.Retrospective cohort study in patients at US Veterans Affairs hospitals who had a coronary stent placed between January 1, 2000, and December 31, 2010, and underwent noncardiac surgery within the following 24 months. The association between the indication for stent and postoperative MACE rates was examined using logistic regression to control for patient and procedure factors.Three subgroups of stent indication were examined: (1) myocardial infarction (MI); (2) unstable angina; and (3) revascularization not associated with acute coronary syndrome (non-ACS).Composite 30-day postoperative MACE rates including all-cause mortality, MI, or revascularization.Among 26?661 patients (median [IQR] age, 68 [61.0-76.0] years; 98.4% male; 88.1% white) who underwent 41?815 surgical procedures within 24 months following coronary stent placement, the stent indication was MI in 32.8% of the procedures, unstable angina in 33.8%, and non-ACS in 33.4%. Postoperative MACE rates were significantly higher in the MI group (7.5%) compared with the unstable angina (2.7%) and non-ACS (2.6%) groups (P?

SUBMITTER: Holcomb CN 

PROVIDER: S-EPMC4893305 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Association of Coronary Stent Indication With Postoperative Outcomes Following Noncardiac Surgery.

Holcomb Carla N CN   Hollis Robert H RH   Graham Laura A LA   Richman Joshua S JS   Valle Javier A JA   Itani Kamal M KM   Maddox Thomas M TM   Hawn Mary T MT  

JAMA surgery 20160501 5


<h4>Importance</h4>Current guidelines for delaying surgery after coronary stent placement are based on stent type. However, the indication for the stent may be an important risk factor for postoperative major adverse cardiac events (MACE).<h4>Objective</h4>To determine whether the clinical indication for a coronary stent is associated with postoperative MACE.<h4>Design, setting, and participants</h4>Retrospective cohort study in patients at US Veterans Affairs hospitals who had a coronary stent  ...[more]

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