Ontology highlight
ABSTRACT:
SUBMITTER: Su Y
PROVIDER: S-EPMC4893649 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Su Yuan Y Zhu Liping L Yu Xiangyuan X Cai Lei L Lu Yankai Y Zhang Jiwei J Li Tongfei T Li Jiansha J Xia Jingyan J Xu Feng F Hu Qinghua Q
Theranostics 20160524 8
Increased cholinergic activity has been highlighted in the pathogenesis of airway hyperresponsiveness, and alternations of mitochondrial structure and function appear to be involved in many lung diseases including airway hyperresponsiveness. It is crucial to clarify the cause-effect association between mitochondrial dysfunction and cholinergic hyperactivity in the pathogenesis of airway hyperresponsiveness. Male SD rats and cultured airway epithelial cells were exposed to cigarette smoke plus li ...[more]