Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC4894434 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Zhang Qiuxiang Q Lu Rongwen R Wang Benquan B Messinger Jeffrey D JD Curcio Christine A CA Yao Xincheng X
Scientific reports 20150422
Transient intrinsic optical signal (IOS) changes have been observed in retinal photoreceptors, suggesting a unique biomarker for eye disease detection. However, clinical deployment of IOS imaging is challenging due to unclear IOS sources and limited signal-to-noise ratios (SNRs). Here, by developing high spatiotemporal resolution optical coherence tomography (OCT) and applying an adaptive algorithm for IOS processing, we were able to record robust IOSs from single-pass measurements. Transient IO ...[more]