BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis.
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ABSTRACT:
SUBMITTER: Zheleznyakova GY
PROVIDER: S-EPMC4895990 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
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BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis.
Zheleznyakova Galina Y GY Cao Hao H Schiöth Helgi B HB
Behavioral and brain functions : BBF 20160606 1
Brain-derived neurotrophic factor (BDNF) plays an important role in nervous system development and function and it is well established that BDNF is involved in the pathogenesis of a wide range of psychiatric disorders. Recently, numerous studies have associated the DNA methylation level of BDNF promoters with certain psychiatric phenotypes. In this review, we summarize data from current literature as well as from our own analysis with respect to the correlation of BDNF methylation changes with p ...[more]
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