Ontology highlight
ABSTRACT:
SUBMITTER: Dowall SD
PROVIDER: S-EPMC4896484 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Dowall Stuart D SD Graham Victoria A VA Rayner Emma E Hunter Laura L Watson Robert R Taylor Irene I Rule Antony A Carroll Miles W MW Hewson Roger R
PloS one 20160607 6
Crimean-Congo Haemorrhagic Fever (CCHF) is a severe tick-borne disease, endemic in many countries in Africa, the Middle East, Eastern Europe and Asia. There is no approved vaccine currently available against CCHF. The most promising candidate, which has previously been shown to confer protection in the small animal model, is a modified Vaccinia Ankara virus vector expressing the CCHF viral glycoprotein (MVA-GP). It has been shown that MVA-GP induces both humoral and cellular immunogenicity. In t ...[more]