Ontology highlight
ABSTRACT:
SUBMITTER: Reynolds G
PROVIDER: S-EPMC4896612 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Reynolds Gary G Cooles Faye A H FA Isaacs John D JD Hilkens Catharien M U CM
Human vaccines & immunotherapeutics 20140217 4
Novel treatments in development for rheumatoid arthritis target 3 broad areas: cytokines, cells, and signaling pathways. Therapies from each domain share common advantages (for example previously demonstrated efficacy, potential long-term immunomodulation, and oral administration respectively) that have stimulated research in each area but also common obstacles to their development. In this review recent progress in each area will be discussed alongside the factors that have impeded their path t ...[more]