Relationship between Metabolic Fluxes and Sequence-Derived Properties of Enzymes.
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ABSTRACT:
SUBMITTER: Zikmanis P
PROVIDER: S-EPMC4897147 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Relationship between Metabolic Fluxes and Sequence-Derived Properties of Enzymes.
Zikmanis Peteris P Kampenusa Inara I
International scholarly research notices 20141029
Metabolic fluxes are key parameters of metabolic pathways being closely related to the kinetic properties of enzymes, thereby could be dependent on. This study examines possible relationships between the metabolic fluxes and the physical-chemical/structural features of enzymes from the yeast Saccharomyces cerevisiae glycolysis pathway. Metabolic fluxes were quantified by the COPASI tool using the kinetic models of Hynne and Teusink at varied concentrations of external glucose. The enzyme sequenc ...[more]
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