Ontology highlight
ABSTRACT:
SUBMITTER: Sanzarello I
PROVIDER: S-EPMC4897302 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
International scholarly research notices 20141029
Duchenne muscular dystrophy is a progressive disease with loss of ambulation at around 9-10 years of age, followed, if untreated, by development of scoliosis, respiratory insufficiency, and death in the second decade of life. This review highlights the natural history of the disease, in particular, with regard to the development of the spinal deformity and how this complication has been modified by surgical interventions and overall by corticosteroid treatment. The beneficial effect of corticost ...[more]