Evolutionary consequences of polyploidy in prokaryotes and the origin of mitosis and meiosis.

ABSTRACT:

Background

The origin of eukaryote-specific traits such as mitosis and sexual reproduction remains disputable. There is growing evidence that both mitosis and eukaryotic sex (i.e., the alternation of syngamy and meiosis) may have already existed in the basal eukaryotes. The mating system of the halophilic archaeon Haloferax volcanii probably represents an intermediate stage between typical prokaryotic and eukaryotic sex. H. volcanii is highly polyploid, as well as many other Archaea. Here, we use computer simulation to explore genetic and evolutionary outcomes of polyploidy in amitotic prokaryotes and its possible role in the origin of mitosis, meiosis and eukaryotic sex.

Results

Modeling suggests that polyploidy can confer strong short-term evolutionary advantage to amitoti

SUBMITTER: Markov AV 

PROVIDER: S-EPMC4898445 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature