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Genetic diversity, seasonality and transmission network of human metapneumovirus: identification of a unique sub-lineage of the fusion and attachment genes.

ABSTRACT: Human metapneumovirus (HMPV) is an important viral respiratory pathogen worldwide. Current knowledge regarding the genetic diversity, seasonality and transmission dynamics of HMPV among adults and children living in tropical climate remains limited. HMPV prevailed at 2.2% (n?=?86/3,935) among individuals presented with acute respiratory tract infections in Kuala Lumpur, Malaysia between 2012 and 2014. Seasonal peaks were observed during the northeast monsoon season (November-April) and correlated with higher relative humidity and number of rainy days (P?

SUBMITTER: Chow WZ

PROVIDER: S-EPMC4899729 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Genetic diversity, seasonality and transmission network of human metapneumovirus: identification of a unique sub-lineage of the fusion and attachment genes.

Chow Wei Zhen WZ Chan Yoke Fun YF Oong Xiang Yong XY Ng Liang Jie LJ Nor'E Siti Sarah SS Ng Kim Tien KT Chan Kok Gan KG Hanafi Nik Sherina NS Pang Yong Kek YK Kamarulzaman Adeeba A Tee Kok Keng KK

Scientific reports 20160609

Human metapneumovirus (HMPV) is an important viral respiratory pathogen worldwide. Current knowledge regarding the genetic diversity, seasonality and transmission dynamics of HMPV among adults and children living in tropical climate remains limited. HMPV prevailed at 2.2% (n = 86/3,935) among individuals presented with acute respiratory tract infections in Kuala Lumpur, Malaysia between 2012 and 2014. Seasonal peaks were observed during the northeast monsoon season (November-April) and correlate ...[more]

PMID: 27279080

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