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Genomic study of adolescent idiopathic scoliosis in Japan.

ABSTRACT: Adolescent idiopathic scoliosis (AIS) is a common disease. It is a multi-factorial (polygenic) disease controlled by genetic and environmental factors. Studies searching for genetic factors of AIS using linkage and association analyses have been conducted and several susceptibility genes have been reported. This paper reviews the recent progress in the genome-wide association study of AIS in Japan and comments on its future task.

SUBMITTER: Ikegawa S

PROVIDER: S-EPMC4900236 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Genomic study of adolescent idiopathic scoliosis in Japan.

Ikegawa Shiro S

Scoliosis and spinal disorders 20160401

Adolescent idiopathic scoliosis (AIS) is a common disease. It is a multi-factorial (polygenic) disease controlled by genetic and environmental factors. Studies searching for genetic factors of AIS using linkage and association analyses have been conducted and several susceptibility genes have been reported. This paper reviews the recent progress in the genome-wide association study of AIS in Japan and comments on its future task. ...[more]

PMID: 27299157

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