Ontology highlight
ABSTRACT:
SUBMITTER: Yasun E
PROVIDER: S-EPMC4902113 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Nanoscale 20150520 22
Aptamer-conjugated gold nanorods (AuNRs) are excellent candidates for targeted hyperthermia therapy of cancer cells. However, in high concentrations of AuNRs, aptamer conjugation alone fails to result in highly cell-specific AuNRs due to the presence of positively charged cetyltrimethylammonium bromide (CTAB) as a templating surfactant. Besides causing nonspecific electrostatic interactions with the cell surfaces, CTAB can also be cytotoxic, leading to uncontrolled cell death. To avoid the nonsp ...[more]