Ontology highlight
ABSTRACT:
SUBMITTER: Cao S
PROVIDER: S-EPMC4902161 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Nucleic acids and molecular biology 20120407
In spite of the success of computational methods for predicting RNA secondary structure, the problem of predicting RNA tertiary structure folding remains. Low-resolution structural models show promise as they allow for rigorous statistical mechanical computation for the conformational entropies, free energies, and the coarse-grained structures of tertiary folds. Molecular dynamics refinement of coarse-grained structures leads to all-atom 3D structures. Modeling based on statistical mechanics pri ...[more]