Neural Processing of Emotional Musical and Nonmusical Stimuli in Depression.

ABSTRACT:

Background

Anterior cingulate cortex (ACC) and striatum are part of the emotional neural circuitry implicated in major depressive disorder (MDD). Music is often used for emotion regulation, and pleasurable music listening activates the dopaminergic system in the brain, including the ACC. The present study uses functional MRI (fMRI) and an emotional nonmusical and musical stimuli paradigm to examine how neural processing of emotionally provocative auditory stimuli is altered within the ACC and striatum in depression.

Method

Nineteen MDD and 20 never-depressed (ND) control participants listened to standardized positive and negative emotional musical and nonmusical stimuli during fMRI scanning and gave subjective ratings of valence and arousal following scanning.

Results

SUBMITTER: Lepping RJ 

PROVIDER: S-EPMC4902194 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature