Ontology highlight
ABSTRACT:
SUBMITTER: Reinisch KM
PROVIDER: S-EPMC4902782 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Reinisch Karin M KM De Camilli Pietro P
Biochimica et biophysica acta 20151210 8 Pt B
SMP-domains are found in proteins that localize to membrane contact sites. Elucidation of the properties of these proteins gives clues as to the molecular bases underlying processes that occur at such sites. Described here are recent discoveries concerning the structure, function, and regulation of the Extended-Synaptotagmin proteins and ERMES complex subunits, SMP-domain proteins at endoplasmic reticulum (ER)-plasma membrane and ER-mitochondrial contacts, respectively. They act as tethers contr ...[more]