Ontology highlight
ABSTRACT:
SUBMITTER: Kraguljac NV
PROVIDER: S-EPMC4903060 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Kraguljac Nina Vanessa NV Kraguljac Nina Vanessa NV White David Matthew DM Hadley Nathan N Hadley Jennifer Ann JA Ver Hoef Lawrence L Davis Ebony E Lahti Adrienne Carol AC
Schizophrenia bulletin 20160212 4
To better characterize hippocampal pathophysiology in schizophrenia, we conducted a longitudinal study evaluating hippocampal functional connectivity during resting state, using seeds prescribed in its anterior and posterior regions. We enrolled 34 unmedicated patients with schizophrenia or schizoaffective disorder (SZ) and 34 matched healthy controls. SZ were scanned while off medication, then were treated with risperidone for 6 weeks and re-scanned (n = 22). Group differences in connectivity, ...[more]