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Flexible Octopus-Shaped Hydrogel Particles for Specific Cell Capture.


ABSTRACT: Multiarm hydrogel microparticles with varying geometry are fabricated to specifically capture cells expressing epithelial cell adhesion molecule. Results show that particle shape influences cell-capture efficiency due to differences in surface area, hydrodynamic effects, and steric constraints. These findings can lead to improved particle design for cell separation and diagnostic applications.

SUBMITTER: Chen L 

PROVIDER: S-EPMC4903076 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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