Flexible Octopus-Shaped Hydrogel Particles for Specific Cell Capture.
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ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC4903076 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
Flexible Octopus-Shaped Hydrogel Particles for Specific Cell Capture.
Chen Lynna L An Harry Z HZ Haghgooie Ramin R Shank Aaron T AT Martel Joseph M JM Toner Mehmet M Doyle Patrick S PS
Small (Weinheim an der Bergstrasse, Germany) 20160301 15
Multiarm hydrogel microparticles with varying geometry are fabricated to specifically capture cells expressing epithelial cell adhesion molecule. Results show that particle shape influences cell-capture efficiency due to differences in surface area, hydrodynamic effects, and steric constraints. These findings can lead to improved particle design for cell separation and diagnostic applications. ...[more]
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