Identifying gene expression modules that define human cell fates.
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ABSTRACT:
SUBMITTER: Germanguz I
PROVIDER: S-EPMC4903895 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
Identifying gene expression modules that define human cell fates.
Germanguz I I Listgarten J J Cinkornpumin J J Solomon A A Gaeta X X Lowry W E WE
Stem cell research 20160413 3
Using a compendium of cell-state-specific gene expression data, we identified genes that uniquely define cell states, including those thought to represent various developmental stages. Our analysis sheds light on human cell fate through the identification of core genes that are altered over several developmental milestones, and across regional specification. Here we present cell-type specific gene expression data for 17 distinct cell states and demonstrate that these modules of genes can in fact ...[more]
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