Ontology highlight
ABSTRACT:
SUBMITTER: Chen R
PROVIDER: S-EPMC4904206 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Chen Ru R Wang Jing J Tang Shaowen S Zhang Yuan Y Lv Xiaozhen X Wu Shanshan S Yang Zhirong Z Xia Yinyin Y Chen Dafang D Zhan Siyan S
Scientific reports 20160613
Evidence indicates that the polymorphisms in bile salt export pump (BSEP, encoded by ABCB11) may play an important role in the development of anti-tuberculosis drug-induced liver injury (ATDILI) and we aim to investigate the association between genetic variants of ABCB11 and the risk of ATDILI in a Chinese cohort. A total of 89 tuberculosis patients with ATDILI and 356 matched ATDILI -free patients constituted cases and controls. Genetic polymorphisms of ABCB11 were determined by TaqMan single-n ...[more]