Structurally Distinct Cation Channelrhodopsins from Cryptophyte Algae.
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ABSTRACT:
SUBMITTER: Govorunova EG
PROVIDER: S-EPMC4906376 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Publications
Structurally Distinct Cation Channelrhodopsins from Cryptophyte Algae.
Govorunova Elena G EG Sineshchekov Oleg A OA Spudich John L JL
Biophysical journal 20160524 11
Microbial rhodopsins are remarkable for the diversity of their functional mechanisms based on the same protein scaffold. A class of rhodopsins from cryptophyte algae show close sequence homology with haloarchaeal rhodopsin proton pumps rather than with previously known channelrhodopsins from chlorophyte (green) algae. In particular, both aspartate residues that occupy the positions of the chromophore Schiff base proton acceptor and donor, a hallmark of rhodopsin proton pumps, are conserved in th ...[more]
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