Ontology highlight
ABSTRACT:
SUBMITTER: Miao Z
PROVIDER: S-EPMC4906479 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
ChemistryOpen 20160113 2
Phosphine-based detection strategies for both nitroxyl (HNO) and S-nitrosothiols (RSNO) were investigated and compared. Phosphorus NMR studies show that azaylides derived from HNO or organic RSNO efficiently participate in subsequent reductive ligation required for fluorescence generation in properly substituted substrates. S-Azaylides derived from biological RSNO containing free amine and carboxylic acid groups primarily yield phosphine oxides suggesting these groups facilitate nonligation path ...[more]