Ontology highlight
ABSTRACT:
SUBMITTER: Schultheis AM
PROVIDER: S-EPMC4909128 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Journal of the National Cancer Institute 20160201 6
Synchronous early-stage endometrioid endometrial carcinomas (EECs) and endometrioid ovarian carcinomas (EOCs) are associated with a favorable prognosis and have been suggested to represent independent primary tumors rather than metastatic disease. We subjected sporadic synchronous EECs/EOCs from five patients to whole-exome massively parallel sequencing, which revealed that the EEC and EOC of each case displayed strikingly similar repertoires of somatic mutations and gene copy number alterations ...[more]