Ontology highlight
ABSTRACT:
SUBMITTER: Burghardt EL
PROVIDER: S-EPMC4909304 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Burghardt Elliot L EL Flenker Katie S KS Clark Karen C KC Miguel Jeff J Ince Dilek D Winokur Patricia P Ford Bradley B McNamara James O JO
PloS one 20160615 6
S. aureus bacteremia (SAB) is a common condition with high rates of morbidity and mortality. Current methods used to diagnose SAB take at least a day, and often longer. Patients with suspected bacteremia must therefore be empirically treated, often unnecessarily, while assay results are pending. In this proof-of-concept study, we describe an inexpensive assay that detects SAB via the detection of micrococcal nuclease (an enzyme secreted by S. aureus) in patient plasma samples in less than three ...[more]