Ontology highlight
ABSTRACT:
SUBMITTER: Rohm M
PROVIDER: S-EPMC4910301 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Data in brief 20160602
This data article focuses on the production of monoclonal antibodies (mAb) and their fragments Fab and F(ab')2. Here, we present the data of an optimization protocol to improve the product yield of a hybridoma cell process using a Design of Experiment (DoE) strategy. Furthermore, the data of the evaluated conditions were used to test feeding strategies in shake flasks. They were verified in controlled 2 L fed-batch bioreactor processes. Supplementing the culture medium with human insulin-like gr ...[more]