Ontology highlight
ABSTRACT:
SUBMITTER: Smith CJ
PROVIDER: S-EPMC4910827 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Glia 20160331 7
In the mature vertebrate nervous system, central and peripheral nervous system (CNS and PNS, respectively) GLIA myelinate distinct motor axon domains at the motor exit point transition zone (MEP TZ). How these cells preferentially associate with and myelinate discrete, non-overlapping CNS versus PNS axonal segments, is unknown. Using in vivo imaging and genetic cell ablation in zebrafish, we demonstrate that radial glia restrict migration of PNS glia into the spinal cord during development. Prio ...[more]