Magnetoelectric 'spin' on stimulating the brain.

ABSTRACT:

Aim

The in vivo study on imprinting control region mice aims to show that magnetoelectric nanoparticles may directly couple the intrinsic neural activity-induced electric fields with external magnetic fields.

Methods

Approximately 10 µg of CoFe2O4-BaTiO3 30-nm nanoparticles have been intravenously administrated through a tail vein and forced to cross the blood-brain barrier via a d.c. field gradient of 3000 Oe/cm. A surgically attached two-channel electroencephalography headmount has directly measured the modulation of intrinsic electric waveforms by an external a.c. 100-Oe magnetic field in a frequency range of 0-20 Hz.

Results

The modulated signal has reached the strength comparable to that due the regular neural activity.

Conclusion

The study opens a pathway

SUBMITTER: Guduru R 

PROVIDER: S-EPMC4910966 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature