Ontology highlight
ABSTRACT:
SUBMITTER: Sollberger G
PROVIDER: S-EPMC4911059 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20160616 6
Neutrophils are essential innate immune cells whose responses are crucial in the clearance of invading pathogens. Neutrophils can respond to infection by releasing neutrophil extracellular traps (NETs). NETs are formed of chromatin and specific granular proteins and are released after execution of a poorly characterized cell death pathway. Here, we show that NET formation induced by PMA or Candida albicans is independent of RNA polymerase II and III-mediated transcription as well as of protein s ...[more]