Ontology highlight
ABSTRACT:
SUBMITTER: Kamkaew A
PROVIDER: S-EPMC4912020 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Kamkaew Anyanee A Sun Haiyan H England Christopher G CG Cheng Liang L Liu Zhuang Z Cai Weibo W
Chemical communications (Cambridge, England) 20160501 43
A small luciferase protein (Nluc) was conjugated to QDs as a bioluminescence resonance energy transfer (BRET) pair. The conjugate showed 76% BRET efficiency and lymph node mapping was successfully performed. The cRGD peptide was conjugated to QD-Nluc for tumor targeting. The self-illuminating QD-Nluc showed excellent energy transfer in a living system and offered an optimal tumor-to-background ratio (>85). ...[more]