Ontology highlight
ABSTRACT:
SUBMITTER: Grigoriadis NG
PROVIDER: S-EPMC4913295 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Grigoriadis Nikolaos G NG Grigoriadis Ioannis G IG Markoula Sofia S Paschopoulos Minas M Zikopoulos Konstantinos K Apostolakopoulos Panagiotis Gr PG Vizirianakis Ioannis S IS Georgiou Ioannis I
American journal of stem cells 20160515 1
Although umbilical cord blood (UCB) hematopoietic stem cell transplantation (UCBT) has emerged as a promising haematological reconstitution therapy for leukemias and other related disorders, the insufficient UCB stem cell dosage still hinders better clinical outcomes. Previous research efforts, by focusing on ex vivo UCB expansion capabilities have sought to benefit from well-known mechanisms of self-renewal characteristics of UCB stem cells. However, the long-term (> 21 days) in vitro culture p ...[more]