Ontology highlight
ABSTRACT:
SUBMITTER: Alamudi SH
PROVIDER: S-EPMC4915154 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Nature communications 20160620
Fluorescence labelling of an intracellular biomolecule in native living cells is a powerful strategy to achieve in-depth understanding of the biomolecule's roles and functions. Besides being nontoxic and specific, desirable labelling probes should be highly cell permeable without nonspecific interactions with other cellular components to warrant high signal-to-noise ratio. While it is critical, rational design for such probes is tricky. Here we report the first predictive model for cell permeabl ...[more]