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ABSTRACT:
SUBMITTER: Houchmandzadeh B
PROVIDER: S-EPMC4915360 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Houchmandzadeh Bahram B Vallade Marcel M
Molecular biology and evolution 20160406 7
The number of substitutions (of nucleotides, amino acids, etc.) that take place during the evolution of a sequence is a stochastic variable of fundamental importance in the field of molecular evolution. Although the mean number of substitutions during molecular evolution of a sequence can be estimated for a given substitution model, no simple solution exists for the variance of this random variable. We show in this article that the computation of the variance is as simple as that of the mean num ...[more]