Ontology highlight
ABSTRACT:
SUBMITTER: He J
PROVIDER: S-EPMC4916159 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Nature methods 20160125 3
Upon illumination, photosensitizer molecules produce reactive oxygen species that can be used for functional manipulation of living cells, including protein inactivation, targeted-damage introduction and cellular ablation. Photosensitizers used to date have been either exogenous, resulting in delivery and removal challenges, or genetically encoded proteins that form or bind a native photosensitizing molecule, resulting in a constitutively active photosensitizer inside the cell. We describe a gen ...[more]