Ontology highlight
ABSTRACT:
SUBMITTER: Li P
PROVIDER: S-EPMC4918506 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Li Peipei P Xing Hua H Zhao Zhenjun Z Yang Zhaoqing Z Cao Yaming Y Li Wenli W Yan Guiyun G Sattabongkot Jetsumon J Cui Liwang L Fan Qi Q
Acta tropica 20150820
Deletion of the Plasmodium falciparum histidine-rich protein 2 (pfhrp2) gene may affect the performance of PfHRP2-based rapid diagnostic tests (RDTs). Here we investigated the genetic diversity of the pfhrp2 gene in clinical parasite isolates collected in recent years from the China-Myanmar border area. Deletion of pfhrp2 has been identified in 4 out of 97 parasite isolates. Sequencing of the pfhrp2 exon2 from 67 isolates revealed a high level of genetic diversity in pfhrp2, which is reflected i ...[more]