A PtdIns(4)P-driven electrostatic field controls cell membrane identity and signalling in plants.

ABSTRACT: Many signalling proteins permanently or transiently localize to specific organelles. It is well established that certain lipids act as biochemical landmarks to specify compartment identity. However, they also influence membrane biophysical properties, which emerge as important features in specifying cellular territories. Such parameters include the membrane inner surface potential, which varies according to the lipid composition of each organelle. Here, we found that the plant plasma membrane (PM) and the cell plate of dividing cells have a unique electrostatic signature controlled by phosphatidylinositol-4-phosphate (PtdIns(4)P). Our results further reveal that, contrarily to other eukaryotes, PtdIns(4)P massively accumulates at the PM, establishing it as a critical hallmark of this membr

SUBMITTER: Simon ML 

PROVIDER: S-EPMC4918763 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature