Ontology highlight
ABSTRACT:
SUBMITTER: Lemon WC
PROVIDER: S-EPMC4918770 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Nature communications 20150811
Understanding how the brain works in tight concert with the rest of the central nervous system (CNS) hinges upon knowledge of coordinated activity patterns across the whole CNS. We present a method for measuring activity in an entire, non-transparent CNS with high spatiotemporal resolution. We combine a light-sheet microscope capable of simultaneous multi-view imaging at volumetric speeds 25-fold faster than the state-of-the-art, a whole-CNS imaging assay for the isolated Drosophila larval CNS a ...[more]