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Genome Sequence of Vaccinia virus Strain Lister-Butantan, a Lister Vaccine Variant Used during a Smallpox Eradication Campaign in Brazil.

ABSTRACT: Here, we report the 187.8-kb genome sequence of Vaccinia virus Lister-Butantan, which was used in Brazil during the WHO smallpox eradication campaign. Its genome showed an average similarity of 98.18% with the original Lister isolate, highlighting the low divergence among related Vaccinia virus vaccine strains, even after several passages in animals and cell culture.

SUBMITTER: Assis F

PROVIDER: S-EPMC4919395 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Genome Sequence of Vaccinia virus Strain Lister-Butantan, a Lister Vaccine Variant Used during a Smallpox Eradication Campaign in Brazil.

Assis Felipe F Trindade Giliane G Drumond Betânia B Frace Mike M Sammons Scott S Emerson Ginny G Li Yu Y Carroll Darin D Batra Dhwani D Abrahão Jonatas J Kroon Erna E

Genome announcements 20160623 3

Here, we report the 187.8-kb genome sequence of Vaccinia virus Lister-Butantan, which was used in Brazil during the WHO smallpox eradication campaign. Its genome showed an average similarity of 98.18% with the original Lister isolate, highlighting the low divergence among related Vaccinia virus vaccine strains, even after several passages in animals and cell culture. ...[more]

PMID: 27340056

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