Ontology highlight
ABSTRACT:
SUBMITTER: Deiana M
PROVIDER: S-EPMC4919647 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Scientific reports 20160624
The photochromic properties of azobenzene, involving conformational changes occurring upon interaction with light, provide an excellent tool to establish new ways of selective regulation applied to biosystems. We report here on the binding of two water-soluble 4-(phenylazo)benzoic acid derivatives (Azo-2N and Azo-3N) with double stranded DNA and demonstrate that the photoisomerization of Azo-3N leads to changes in DNA structure. In particular, we show that stabilization and destabilization of th ...[more]