Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex.

ABSTRACT: Bioresorbable silicon electronics technology offers unprecedented opportunities to deploy advanced implantable monitoring systems that eliminate risks, cost and discomfort associated with surgical extraction. Applications include postoperative monitoring and transient physiologic recording after percutaneous or minimally invasive placement of vascular, cardiac, orthopaedic, neural or other devices. We present an embodiment of these materials in both passive and actively addressed arrays of bioresorbable silicon electrodes with multiplexing capabilities, which record in vivo electrophysiological signals from the cortical surface and the subgaleal space. The devices detect normal physiologic and epileptiform activity, both in acute and chronic recordings. Comparative studies show sensor perf

SUBMITTER: Yu KJ 

PROVIDER: S-EPMC4919903 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature