Ontology highlight
ABSTRACT:
SUBMITTER: Royer S
PROVIDER: S-EPMC4919905 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Royer Sébastien S Zemelman Boris V BV Losonczy Attila A Kim Jinhyun J Chance Frances F Magee Jeffrey C JC Buzsáki György G
Nature neuroscience 20120325 5
A consortium of inhibitory neurons control the firing patterns of pyramidal cells, but their specific roles in the behaving animal are largely unknown. We performed simultaneous physiological recordings and optogenetic silencing of either perisomatic (parvalbumin (PV) expressing) or dendrite-targeting (somatostatin (SOM) expressing) interneurons in hippocampal area CA1 of head-fixed mice actively moving a treadmill belt rich with visual-tactile stimuli. Silencing of either PV or SOM interneurons ...[more]