Ontology highlight
ABSTRACT:
SUBMITTER: Gordon D
PROVIDER: S-EPMC4920363 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20160401 6281
Accurate sequence and assembly of genomes is a critical first step for studies of genetic variation. We generated a high-quality assembly of the gorilla genome using single-molecule, real-time sequence technology and a string graph de novo assembly algorithm. The new assembly improves contiguity by two to three orders of magnitude with respect to previously released assemblies, recovering 87% of missing reference exons and incomplete gene models. Although regions of large, high-identity segmenta ...[more]