Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen KB
PROVIDER: S-EPMC4922149 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Nguyen Kim B KB Sreelatha Anju A Durrant Eric S ES Lopez-Garrido Javier J Muszewska Anna A Dudkiewicz Małgorzata M Grynberg Marcin M Yee Samantha S Pogliano Kit K Tomchick Diana R DR Pawłowski Krzysztof K Dixon Jack E JE Tagliabracci Vincent S VS
Proceedings of the National Academy of Sciences of the United States of America 20160516 25
The modification of proteins by phosphorylation occurs in all life forms and is catalyzed by a large superfamily of enzymes known as protein kinases. We recently discovered a family of secretory pathway kinases that phosphorylate extracellular proteins. One member, family with sequence similarity 20C (Fam20C), is the physiological Golgi casein kinase. While examining distantly related protein sequences, we observed low levels of identity between the spore coat protein H (CotH), and the Fam20C-re ...[more]