Ontology highlight
ABSTRACT:
SUBMITTER: Hiraoka T
PROVIDER: S-EPMC4922514 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Hiraoka Takehiro T Hirota Yasushi Y Saito-Fujita Tomoko T Matsuo Mitsunori M Egashira Mahiro M Matsumoto Leona L Haraguchi Hirofumi H Dey Sudhansu K SK Furukawa Katsuko S KS Fujii Tomoyuki T Osuga Yutaka Y
JCI insight 20160601 8
Although a close connection between uterine regeneration and successful pregnancy in both humans and mice has been consistently observed, its molecular basis remains unclear. We here established a mouse model of decellularized uterine matrix (DUM) transplantation. Resected mouse uteri were processed with SDS to make DUMs without any intact cells. DUMs were transplanted into the mouse uteri with artificially induced defects, and all the uterine layers were recovered at the DUM transplantation sit ...[more]